Explore the revolutionary genome editing technologies including CRISPR-Cas9, ZFNs, TALENs, RNAi, and Cre-loxP that are transforming biotechnology and medicine.
Discover how TP53 missense mutations act as molecular double agents in myeloid malignancies, sabotaging our cellular defenses through dominant-negative effects.
Explore how Cas-OFFinder, Cas-Designer, and Cas-Analyzer form an essential toolkit for precise CRISPR gene editing, addressing off-target effects and improving genetic engineering outcomes.
Explore how CRISPR-Cas9 gene editing technology is transforming sleep medicine and offering new hope for treating genetic sleep disorders.
Explore how CDKN2A gene mutations disrupt cell cycle regulation and drive melanoma development through inherited and acquired genetic changes.
Explore how gene editing technologies like CRISPR are revolutionizing agriculture through targeted breeding and de novo domestication of crops.
Explore how nanoparticle delivery systems are revolutionizing cancer gene therapy by enabling precise delivery of genetic treatments directly to cancer cells.
Explore the Hedgehog-GLI signaling pathway, its role in embryonic development, and how its dysregulation leads to cancer and other diseases.
Explore how network biology is revolutionizing our understanding of cellular interactions and disease mechanisms through advanced computational approaches.
Explore how gene editing technologies like CRISPR, base editing, and prime editing are transforming cystic fibrosis treatment by correcting genetic mutations at their source.